Advances in Bladder Research by Tung-Tien Sun, Feng-Xia Liang, Xue-Ru Wu (auth.), Laurence

By Tung-Tien Sun, Feng-Xia Liang, Xue-Ru Wu (auth.), Laurence S. Baskin, Simon W. Hayward (eds.)

The objective of Bladder learn Congress, San Francisco, California, April 23-25, 1998, used to be to supply a discussion board for authoritative investigators who're actively fascinated about a number of the disciplines which outline the top edges of bladder examine. it is necessary for such investigators to proceed to fulfill usually for the aim of discussing the most recent advancements of their person fields, to research the importance of present study, to debate new strategies for unresolved difficulties, to severely overview present theories, and to increase new theories and techniques as wanted. the 2 and a part day assembly used to be geared up into 5 part day periods, with every one consultation encompassing considered one of 5 issues: (1) Epithelial-Mesenchymal Interactions; (2) Ex­ tracellular Matrix and Muscle; (3) Nerves and Pharmacology; (4) an infection and Immunol­ ogy; and (5) Oncology. every one consultation was once brought by means of a moderator by way of 5 to 6 invited specialist audio system with time for wide interplay from the members. late-afternoon poster classes allowed extra interactions among investigators. This ebook files the lawsuits of the Bladder study Congress. it truly is organ­ ized into the 5 half-day periods of the assembly with moderators evaluation and an edited transcription of discussions that each one presentation. i need to thank Sarah Burke and the workplace of continuous clinical schooling, USCF; Joanne Hayward, Editorial Assistant; and Miriam Escamilla, Administrative Assis­ tant. i am hoping you discover this source beneficial. Laurence S. Baskin, M.D.

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72: 355, 1984. 38. : Urothelium-specific antibody and lectin surface mapping of bladder urothelium. Histochem. , 14: 755, 1982. 39. : Identification of an 85-100 kDa glycoprotein as a cell surface marker for an advanced stage ofurothelial differentiation: association with the inter-plaque ('hinge') area. , 1: 4, 1992. 40. , Schermer A.. Cooper D .. : Classification, expression, and possible mechanisms of evolution of mammalian epithelial keratins: a unifying model. , Topp we. D. (eds), Cold Spring Harbor Laboratory.

13 These polymers have many desirable features; they are biocompatible, processable, and biodegradable. Degradation occurs by hydrolysis and the time sequence can be varied from weeks to over a year by manipulating the ratio of monomers and by varying the processing conditions. These polymers can be readily formed into a variety of structures, including small diameter fibers and porous films. The porosity, pore size distribution and continuity dictate the interaction of the biomaterials and transplanted cells with the host tissue.

Group B (n=6) underwent reconstruction with a cellfree bladder shaped biodegradable polymer. Group C (n=6) underwent reconstruction using a bladder shaped biodegradable polymer that delivered autologous urothelial cells and smooth muscle cells. The cell populations had been separately expanded from a previously harvested autologous bladder biopsy. Preoperative and postoperative urodynamic and radiographic studies were performed serially. Animals were sacrificed at I, 2, 3, 4, 6, and II months postoperatively.

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